| 发明名称 | Cellobiohydrolase variants | ||
| 摘要 | The present invention relates to cellobiohydrolase variants having improved thermostability in comparison to wild-type CBH2a. | ||
| 申请公布号 | US9260705(B2) | 申请公布日期 | 2016.02.16 |
| 申请号 | US201414588231 | 申请日期 | 2014.12.31 |
| 申请人 | Codexis, Inc. | 发明人 | Baidyaroy Dipnath;Clark Louis;Elgart David;Voladri Rama;Zhang Xiyun |
| 分类号 | C12N9/42;C12N1/20;C12N15/00;C07H21/04;C12P19/14;C12P19/02;C12N15/80;C12P7/14;C12P7/16;C12P7/18;C12P7/20;C12P7/46;C12P7/48;C12P7/54;C12P7/56;C12P7/58;C12P13/14 | 主分类号 | C12N9/42 |
| 代理机构 | Codexis, Inc. | 代理人 | Codexis, Inc. |
| 主权项 | 1. A recombinant polynucleotide that comprises a nucleic acid sequence encoding a cellobiohydrolase type 2a (CBH2a) variant comprising at least about 90% sequence identity to SEQ ID NO:1 and comprising an amino acid substitution, relative to SEQ ID NO:1, at one or more positions selected from 15, 204, and 340, wherein the position is numbered with reference to SEQ ID NO:1. | ||
| 地址 | Redwood City CA US | ||