| 发明名称 |
4,6-diaminopyrimidine stimulators of soluble guanylate cyclase |
| 摘要 |
The present invention relates to new 4,6-diaminopyrimidine stimulators of soluble guanylate cyclase, pharmaceutical compositions thereof, and methods of use thereof; |
| 申请公布号 |
US9260424(B2) |
申请公布日期 |
2016.02.16 |
| 申请号 |
US201012911268 |
申请日期 |
2010.10.25 |
| 申请人 |
Auspex Pharmaceuticals, Inc. |
发明人 |
Rao Tadimeti;Zhang Chengzhi |
| 分类号 |
A61K31/506;C07D403/14;A61P11/00;A61P19/10;A61P9/10;A61P9/12;A61P25/06;A61P13/12;A61P3/10;C07D471/04;A61K31/437;A61K45/06 |
主分类号 |
A61K31/506 |
| 代理机构 |
|
代理人 |
Bennett Dennis A.;Hathaway Cynthia |
| 主权项 |
1. A pharmaceutical composition comprising a compound selected from the group consisting of: wherein each position represented as D has deuterium enrichment of no less than about 10%; together with a pharmaceutically acceptable carrier, wherein said pharmaceutical composition is a tablet or capsule. |
| 地址 |
La Jolla CA US |
