| 发明名称 | Crystal forms of saxagliptin | ||
| 摘要 | The present invention relates to novel polymorphic forms of Saxagliptin Hydrochloride. The present invention also relates to methods of making polymorphic forms of Saxagliptin Hydrochloride. | ||
| 申请公布号 | US9260389(B2) | 申请公布日期 | 2016.02.16 |
| 申请号 | US201314044204 | 申请日期 | 2013.10.02 |
| 申请人 | SANDOZ AG | 发明人 | Pichler Arthur;Wieser Josef;Langes Christoph;Vukicevic Milica |
| 分类号 | C07D209/52;A61K31/403;A61K45/06 | 主分类号 | C07D209/52 |
| 代理机构 | Manelli Selter PLLC | 代理人 | Melcher Jeffrey S.;Manelli Selter PLLC |
| 主权项 | 1. Crystalline Form I-S of Saxagliptin hydrochloride having a water content of not more than 1.5% w/w and a x-ray powder diffraction pattern comprising peaks at 6.7±0.2, 14.6±0.2, 15.2±0.2, 16.6±0.2 and 17.9±0.2 degrees two-theta and/or having an infrared spectrum comprising peaks at wavenumbers of 2907, 2853, 1637, 1589, 1462, 1391, 1318, 1045, 1014 and 775+/−2 cm-1, wherein the crystalline form is greater than 95% by weight. | ||
| 地址 | Basel CH | ||