Ophthalmic devices for delivery of beneficial agents

摘要

Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.

主权项

1. A method of manufacturing a contact lens, said method comprising:
a) polymerizing a monomer mixture comprising 2-methacryloyloxyethyl phosphorylcholine (MPC) to provide an non-hydrated lens-shaped polymerization product; b) immersing the non-hydrated lens-shaped polymerization product in a package containing a packaging solution comprising an ionic agent; and c) sealing the package, wherein the ionic agent electrostatically attaches to phosphorylcholine groups on the MPC.