| 发明名称 |
SITAGLIPTIN SYNTHESIS |
| 摘要 |
The present invention relates to novel processes for the preparation of enantiomerically enriched .beta.-amino acid derivatives such as .beta.-amino esters useful for the synthesis of enantiomerically enriched biologically active molecules such as sitagliptin. The key step involves the resolution of the racemate with mandelic acid. |
| 申请公布号 |
CA2759077(C) |
申请公布日期 |
2016.02.16 |
| 申请号 |
CA20102759077 |
申请日期 |
2010.05.10 |
| 申请人 |
GENERICS [UK] LIMITED |
发明人 |
GORE, VINAYAK GOVIND;GADAKAR, MAHESHKUMAR;BHOSLE, PRIYANKA;SHINDE, SURESH |
| 分类号 |
C07D487/04;A61K31/4985;A61P3/10;C07C227/16;C07C227/34;C07C229/34 |
主分类号 |
C07D487/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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