发明名称 Device and method for the production of radiochemical compounds
摘要 The invention relates to a device for the preparation of radiochemical compounds. It is provided that the device comprises at least a reaction module, a dosing module, and a storage module, wherein the reaction module has at least one reaction vessel having a closable opening through which substances needed for the preparation of a predetermined radiochemical compound can be introduced into the reaction vessel of the reaction module and through which the prepared radiochemical compound can be removed from the reaction vessel of the reaction module;the dosing module has at least one pipetting head which can be moved relative to the storage module and the reaction module and in x, y, and z directions and also has at least one dosing unit; andat least one reservoir for one of the substances needed for the preparation of the respective radiochemical compound is formed in the storage module.
申请公布号 US9260354(B2) 申请公布日期 2016.02.16
申请号 US201514592283 申请日期 2015.01.08
申请人 ABX ADVANCED CHEMICAL COMPOUNDS GMBH;GeSIM—Gesellschaft für Silizium-Mikrosysteme mbH 发明人 Mueller Marco;Howitz Steffen
分类号 B01J10/00;C07B59/00;B01J19/00;C07H5/02 主分类号 B01J10/00
代理机构 Maier & Maier, PLLC 代理人 Maier & Maier, PLLC
主权项 1. A device for the preparation of radiochemical compounds comprising: at least a reaction module, a dosing module, and a storage module, wherein the reaction module has at least one reaction vessel having a closable opening through which substances needed for the preparation of a predetermined radiochemical compound can be introduced into the reaction vessel of the reaction module and through which the prepared radiochemical compound can be removed from the reaction vessel of the reaction module; the dosing module has at least one pipetting head which can be moved relative to the storage module and the reaction module and in x, y, and z directions and also has one or more dosing units, wherein at least one dosing unit is a triple lumen dosing unit having a first channel for taking up, transporting, and releasing a substance needed for the synthesis of the radio-chemical compound, a second channel for supplying a gas into a reaction vessel and a third channel for draining off gaseous reaction products from the reaction vessel; and at least one reservoir for one of the substances needed for the preparation of the respective radiochemical compound is formed in the storage module; wherein purification means required for the separation of the prepared radiochemical compound from the reaction mixture are integrated into the storage module; and wherein the reaction module, the dosing module, and the storage module are arranged in a hot cell.
地址 Radeberg DE