1H-PYRAZOLO[4,3-C]ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

摘要

THE INVENTION RELATES TO A COMPOUND OF FORMULA (I), WHERE: R? IS A PHENYL GROUP OPTIONALLY SUBSTITUTED BY ONE OR MORE HALOGEN ATOMS; R? IS: A HYDROGEN ATOM OR A HALOGEN ATOM OR A CYANO GROUP; A-C(=O)Y GROUP WHERE Y IS A HYDROGEN ATOM, OR A - NH? OR -OR? GROUP; A -C(=S)NH? GROUP; A ?C(=NH)NH-OH GROUP; A -CH?OH OR -CH?F GROUP; A ?CH=N-OH GROUP; A-CH=CH? OR ?C=C-R? GROUP; A H OR H R? GROUP BEING A HYDROGEN OR (C?-C?)ALKYL GROUP; R? IS A HYDROGEN ATOM OR (C?-C?)ALKYL GROUP; AND R? IS A -NH?, (C?-C?)ALKYL (C?-C?)FLUOROALKYL OR (C?-C?)CYCLOALKYL GROUP.