| 摘要 |
ESTER DERIVATIVES OF 2-AMINO-2-PHENYL-ALKANOL OF GENERAL FORMULA (I) IN WHICH: R1 FORMS WITH R3 AND THE NITROGEN AND CARBON ATOMS TO WHICH THEY ARE RESPECTIVELY ATTACHED, A HETEROCYCLE WITH 4 TO 7 MEMBERS, OPTIONALLY SUBSTITUTED IN THE ? POSITION OF THE NITROGEN ATOM BY ONE OR TWO R? AND Rb RADICALS BEING ABLE TO BE INDEPENDENTLY OF ONE ANOTHER HYDROGEN OR LINEAR OR BRANCHED ALKYL (1 TO 4 C), AND R? IS H OR A-CO-O-CHR?-OCOR? RADICAL FOR WHICH R? IS H OR LINEAR OR BRANCHED ALKYL (1 TO 4C), AND R? IS ALKYL OPTIONALLY SUBSTITUTED BY BENZYLOXYCARBONYLAMINO, ACYLAMINO OR BY THE REMAINDER OF AN AMINO ACID, OR REPRESENTS A HETEROCYCLE, OR R? IS LINEAR OR BRANCHED ALKYL (1 TO 4C), ALKYL (2 TO 4C) SUBSTITUTED BY OH, ALKOXY, ALKYLTHIO, NH?, ALKYLAMINO, DIALKYLAMINO OPTIONALLY FORMING WITH THE NITROGEN ATOM TO WHICH THEY ARE ATTACHED, A HETEROCYCLE WITH 5 OR 6 MEMBERS, IT BEING UNDERSTOOD THAT SAID SUBSTITUTED ALKYL RADICAL IS LINEAR OR BRANCHED AND COMPRISES AT LEAST 2C BETWEEN >N-R? AND THE SUBSTITUENT, UNLESS SPECIFIED OTHERWISE, ALKYL OR ACYL ARE LINEAR OR BRANCHED (1 TO 7C), IN THEIR R OR S FORMS OR THEIR MIXTURES, AS WELL AS ITS PHARMACEUTICALLY ACCEPTABLE SALTS, IF ANY. |
