发明名称 |
FORMULATION COMPRISING PHENYLAMINOPYRIMIDINE DERIVATIVE AS ACTIVE AGENT |
摘要 |
An oral pharmaceutical formulation containing an effective amount of NRC-AN-019 including its pharmaceutically acceptable salts and polymorphs such as Form I, Form II and Form III thereof to improve the bioavailability intended for self-emulsification upon its contact with the gastro-intestinal fluid. The invention also relates to a process for the preparation of oral solution containing NRC-AN-019 in an effective concentration for the better therapy against Chronic Myeloid Leukemia as BCR-ABL tyrosine kinase inhibitor and against other tumors such as head and neck cancer, prostate cancer and the like. |
申请公布号 |
HRP20151382(T1) |
申请公布日期 |
2016.02.12 |
申请号 |
HR2015P001382T |
申请日期 |
2015.12.16 |
申请人 |
NATCO PHARMA LIMITED |
发明人 |
PARVATANENI, DURGA MAHESWARI;YEDLURI, SIDDHARTHA;APPADWEDULA, VENKATA SATYANARAYANA;ADIBHATLA, KALI SATYA BHUJANGA RAO;NANNAPANENI, VENKAIAH CHOWDARY |
分类号 |
A61K31/444;A61K9/08;A61K9/107;A61K9/14;A61K9/48 |
主分类号 |
A61K31/444 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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