| 发明名称 |
MORPHOLINOS, MORPHOLINO UPREGULATING, AND ASSOCIATED METHODS |
| 摘要 |
Various methods and compositions relating to vascular endothelial growth factor receptor 2 (VEGFR2) are provided. In one aspect, a method of increasing expression of the soluble form of VEGFR2 (sVEGFR2) in a subject can include binding an antisense morphoiino to an exon13-intron13 splicing site of VEGFR2 mRNA such that the VEGFR2 niRNA is spliced into a sVEGFR2 isoform, |
| 申请公布号 |
US2016040169(A1) |
申请公布日期 |
2016.02.11 |
| 申请号 |
US201214358572 |
申请日期 |
2012.11.15 |
| 申请人 |
University of Utah Research Foundation |
发明人 |
Ambati Balamurali K.;Uehara Hironori |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of increasing expression of sVEGFR2 in a subject, comprising:
binding an antisense morpholino to an exon13-intron13 splicing site of VEGFR2 mRNA such that the VEGFR2 mRNA is spliced into an sVEGFR2 isoform. |
| 地址 |
Salt Lake City UT US |
