| 发明名称 |
HUMAN FCRN-BINDING MODIFIED ANTIBODIES AND METHODS OF USE. |
| 摘要 |
Herein is reported the use of an antibody comprising an Fc-region with abolished FcRn binding for the transport of a soluble receptor ligand from the eye over the blood-ocular-barrier into the blood circulation. |
| 申请公布号 |
MX2015015061(A) |
申请公布日期 |
2016.02.11 |
| 申请号 |
MX20150015061 |
申请日期 |
2014.04.25 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
JOERG THOMAS REGULA;WOLFGANG SCHAEFER;TILMAN SCHLOTHAUER;GUIDO HARTMANN;MATTHIAS REUTH |
| 分类号 |
C07K16/22;A61K39/395;A61P27/02;C07K16/28;C07K16/46 |
主分类号 |
C07K16/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
