| 发明名称 |
CHANNELRHODOPSIN VARIANTS AND USES THEREOF |
| 摘要 |
CsChrimson light-activated ion channel polypeptides, their encoding polynucleotides, and variants thereof are provided. Methods of introducing and using CsChrimson light activated ion channels and variants thereof for to alter cell activity and function are also provided. |
| 申请公布号 |
US2016039902(A1) |
申请公布日期 |
2016.02.11 |
| 申请号 |
US201514817335 |
申请日期 |
2015.08.04 |
| 申请人 |
Klapoetke Nathan;Chow Brian Yichiun;Boyden Edward;Wong Gane Ka-Shu;Cho Yongku Peter |
发明人 |
Klapoetke Nathan;Chow Brian Yichiun;Boyden Edward;Wong Gane Ka-Shu;Cho Yongku Peter |
| 分类号 |
C07K14/705;A61N5/06;A61K41/00;G01N33/50;C12N13/00 |
主分类号 |
C07K14/705 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A CsChrimson light-activated ion channel polypeptide or variant thereof comprising an amino acid sequence set forth as SEQ ID NO: 1 or an amino acid sequence having at least 70%, 75%, 80%, 85%, 90%, 95%, or 100% identity to amino acids 1-79 of SEQ ID NO:
1 and at least 85%, 90%, 95%, 96%, 97%, 98%, 99% or 100% identity to amino acids 80-315 of SEQ ID NO: 1. |
| 地址 |
Ashburn VA US |
