主权项 |
1. A compound of formula (I): wherein: R1 and R2 are independently selected from the group consisting of: —C1-C4 alkyl, —O—C1-C4 alkyl, —H, and —C1-C4 haloalkyl, and R3 is selected from the group consisting of: —C1-C12 alkyl, —H, —O—C1-C12 alkyl, and —C1-C12 haloalkyl; or R1 and R2 are both —CH3 or R1 and R2 are both —OCH3, and R3 is selected from the group consisting of: n is 0, 1, 2, 3, or 4; R4, R5, R6, and R7 are independently selected from the group consisting of: —C1-C12 haloalkyl, —C(O)—N(R13)(R14), —C1-C12 alkyl, —H, —OH, —C2-C12 alkenyl, —O—C1-C12 alkyl, —O—C(O)—C1-C12 alkyl, —O—C1-C12 haloalkyl, —C6-C10 aryl, —O—C6-C10 aryl, —C1-C6 alkyl-C6-C10 aryl, —O—C1-C6 alkyl-C6-C10 aryl, —N—(R8)(R9), —C(O)—O—C1-C12 alkyl, —S(O)2—C1-C12 alkyl, with the proviso that at least two of R4, R5, R6, and R7 are independently selected from the group consisting of: —H and —CH3; R8 and R9 are independently —H or —C1-C12 alkyl; R13 is —H or —C1-C4 alkyl; R14 is —C1-C12 alkyl optionally substituted with hydroxy, —O—C1-C4, heterocyclyl, aryl, or heteroaryl, or wherein R14 is —C1-C15 alkyl wherein two or more of the carbons in the alkyl group have been replaced by oxygen; m is 0, 1, 2, or 3; and R11 is S or NH; or a stereoisomer, mixture of stereoisomers, solvate, hydrate, or pharmaceutically acceptable salt thereof; with the proviso that the compound is not: or a stereoisomer, mixture of stereoisomers, solvate, hydrate, or pharmaceutically acceptable salt thereof. |