Here, we describe the detailed structure of an intact murine monoclonal anti-hERG1 molecule and the corresponding anti-hERG1 scFv antibody production, obtained after the isolation of the mAb anti-hERG1 VH and VL. Such scFv has the same 5 specificity of the correspondent whole antibody, and thus it is able to recognize the same anti-hERG1 protein, aberrantly expressed in tumours and other diseases
申请公布号
WO2016020483(A1)
申请公布日期
2016.02.11
申请号
WO2015EP68178
申请日期
2015.08.06
申请人
UNIVERSITA' DEGLI STUDI DI FIRENZE;AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI