Perfusion Bioreactor with Tissue Flow Control and Live Imaging Compatibility

摘要

A perfusion bioreactor chamber for engineering a broad spectrum of tissues. The bioreactor allows controlled distribution of fluid through or around scaffolding materials of various shapes, structures and topologies during prolonged periods of cultivation.

主权项

1. A bioreactor culture chamber comprising:
a scaffold; at least one PDMS block; a plurality of manifolds, a plurality of fluid routing blocks configured with fluid routing structural features, the fluid routing blocks configured to be nested within the manifolds; and a case, the case disposed exterior of the scaffold, PDMS block and plurality of manifolds.