MOLECULAR TARGETS FOR HEALING OR TREATING WOUNDS

摘要

The invention relates to at least one molecular target for healing or treating wounds and, in particular chronic, human wounds. The molecular target is nWASP or a protein at least 75% homologous therewith and which retains the same activity as nWASP protein, such as WASP. Further, the invention concerns a novel therapeutic for treating said wounds and a novel gene therapy approach, involving said molecular target, for treating said wounds.

主权项

1. A method for treating a mammalian wound, comprising administering to the wound a topical preparation comprising:
an inhibitor of at least one of a neural Wiskott Aldrich Syndrome Protein (nWASP) gene expression and an nWASP protein activity, or an inhibitor of activity of a protein that is at least 75% homologous to the nWASP protein and that decreases actin assembly; and a pharmaceutically or veterinarily acceptable carrier.