发明名称 |
Removal of serine proteases by treatment with finely divided silicon dioxide |
摘要 |
The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease and/or serine protease zymogen content. Among yet other aspects, the present invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced serine protease and/or serine protease zymogen content. Yet other aspects include methods for treating, managing, and/or preventing a disease comprising the administration of a plasma-derived protein composition having a reduced serine protease or serine protease zymogen content. |
申请公布号 |
AU2011258111(B2) |
申请公布日期 |
2016.02.11 |
申请号 |
AU20110258111 |
申请日期 |
2011.05.26 |
申请人 |
BAXALTA GMBH;BAXALTA INCORPORATED |
发明人 |
TESCHNER, WOLFGANG;SCHWARZ, HANS-PETER;MADLENER, RUTH;SVATOS, SONJA;PLJEVLJAKOVIC, AZRA;WEBER, ALFRED |
分类号 |
C07K16/00;A61K9/00;A61K9/08;A61K38/17;A61K47/18 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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