发明名称 |
DIGITAL MEASUREMENTS FROM TARGETED SEQUENCING |
摘要 |
Disclosed herein are methods, compositions and kits for quantitating one or more specific nucleic acids within a plurality of nucleic acids. In some embodiments, a sequencing library is constructed from enriched probe extension products specific for the specific nucleic acids and sequenced. In some embodiments, the resulting reads are used for removing duplicate reads. In some embodiments, counting of verified probes is used to quantitate or determine the number of specific nucleic acid molecules in the starting nucleic acid sample. |
申请公布号 |
CA2957633(A1) |
申请公布日期 |
2016.02.11 |
申请号 |
CA20152957633 |
申请日期 |
2015.08.06 |
申请人 |
NUGEN TECHNOLOGIES, INC. |
发明人 |
SCOLNICK, JONATHAN;AMORESE, DOUGLAS;HUELGA, STEPHANIE C.;SCHROEDER, BENJAMIN |
分类号 |
C12Q1/68;C40B30/00;C40B30/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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