发明名称 |
ARTICLE COATINGS INCLUDING OLIGOMERIZED POLYPHENOL LAYER AND BIOLOGICAL METHODS OF USE |
摘要 |
Embodiments of the disclosure include coatings comprising an oligomerized polyphenol layer. The oligomerized polyphenol layer can be used as an intermediate coated layer on a medical device that hydrogen bonds to a synthetic or natural polymer, which in turn can be used as a top coat or further associated with another coated layer. The multilayered coatings can provide properties such as hemocompatibility or lubricity. In other embodiments, the oligomerized polyphenol layer is used on a medical device as a hemostatic layer configured to contact blood and promote coagulation. The oligomerized polyphenol layer can also be used on the inner surface (e.g., inner diameter) of a medical device to prevent bacterial adherence. The oligomerized polyphenol layer can also be used on the surface of a in vitro diagnostic article, or a cell culture device to, promote adsorption of a biological molecule. |
申请公布号 |
WO2016022796(A1) |
申请公布日期 |
2016.02.11 |
申请号 |
WO2015US44002 |
申请日期 |
2015.08.06 |
申请人 |
SURMODICS, INC. |
发明人 |
BABCOCK, DAVID E.;LUNDQUIST, SEAN;OPPERMAN, GARY;TORGUSON, ADRIYN;JENTZ, TIM |
分类号 |
A61L27/34;A61K31/7024;A61L29/06;A61L29/08;C08L29/04 |
主分类号 |
A61L27/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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