发明名称 |
ANTIDIABETIC BICYCLIC COMPOUNDS |
摘要 |
Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. |
申请公布号 |
WO2016022448(A1) |
申请公布日期 |
2016.02.11 |
申请号 |
WO2015US43360 |
申请日期 |
2015.08.03 |
申请人 |
MERCK SHARP & DOHME CORP.;CHOBANIAN, HARRY;DEMONG, DUANE;GUO, YAN;PIO, BARBARA;PLUMMER, CHRISTOPHER, W. |
发明人 |
CHOBANIAN, HARRY;DEMONG, DUANE;GUO, YAN;PIO, BARBARA;PLUMMER, CHRISTOPHER, W. |
分类号 |
A61K31/192;A61K31/353;C07D311/20 |
主分类号 |
A61K31/192 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|