| 发明名称 |
MESENCHYMAL STROMAL CELLS AND USES RELATED THERETO |
| 摘要 |
The present invention generally relates to novel preparations of mesenchymal stromal cells (MSCs) derived from hemangioblasts, methods for obtaining such MSCs, and methods of treating a pathology using such MSCs. The methods of the present invention produce substantial numbers of MSCs having a potency-retaining youthful phenotype, which are useful in the treatment of pathologies. |
| 申请公布号 |
US2016038543(A1) |
申请公布日期 |
2016.02.11 |
| 申请号 |
US201414504351 |
申请日期 |
2014.10.01 |
| 申请人 |
Advanced Cell Technology, Inc. |
发明人 |
Kimbrel Erin Anne;Lanza Robert P.;Chu Jianlin;Kouris Nicholas Arthur |
| 分类号 |
A61K35/28;C12N5/0775 |
主分类号 |
A61K35/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical preparation suitable for use in a mammalian patient, comprising at least 106 mesenchymal stromal cells and a pharmaceutically acceptable carrier, wherein the mesenchymal stromal cells have replicative capacity to undergo at least 10 population doublings in cell culture with less than 25 percent of the cells undergoing cell death, senescing or differentiating into non-MSC cells by the tenth doubling. |
| 地址 |
Marlborough MA US |
