MEASURING RESPIRATORY MECHANICS PARAMETERS USING PERTURBATIONS

摘要

According to one embodiment of the present invention, a method of determining respiratory parameters comprises determining a ratio of pressure changes to flow changes induced in the breathing of a patient by an airflow perturbation device at each of a plurality of perturbation frequencies to form a dataset. Resistance, compliance, and inertance parameters of a model of a respiratory system are determined by comparing a predicted frequency dependence of the model to the dataset. Embodiments of the present invention further include a system and computer program product for determining respiratory parameters in substantially the same manners described above.

主权项

1. A system for measuring one or more respiratory parameters comprising:
an airflow perturbation device comprising:
a perturbation mechanism to periodically alter air flow resistance in a pathway at a plurality of frequencies;a pneumotachometer comprising a flow sensor to measure airflow in the pathway; anda pressure sensor to measure a pressure in the pathway; and a computing system comprising at least one processor configured to:
receive data from the flow sensor and pressure sensor and determine a ratio of pressure changes to flow changes induced by the airflow perturbation device at each of the plurality of perturbation frequencies to form a dataset; anddetermine at least one respiratory parameter by comparing a predicted frequency dependence to the dataset.