发明名称 |
CELL SORTING METHOD |
摘要 |
The invention provides a method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells by contacting a pigment epithelium-derived factor with the differentiated cell population to induce apoptosis of the undifferentiated cells. The invention also provides an agent for cell transplantation therapy, containing a differentiated cell population substantially free of an undifferentiated cell, which is obtained by the method, as well as an agent for inducing apoptosis of an undifferentiated cell, containing a pigment epithelium-derived factor, and combined use of the aforementioned agent for cell transplantation therapy and the aforementioned agent for inducing apoptosis. |
申请公布号 |
US2016040123(A1) |
申请公布日期 |
2016.02.11 |
申请号 |
US201414780324 |
申请日期 |
2014.03.25 |
申请人 |
FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION |
发明人 |
KANEMURA Hoshimi;GO Masahiro;KAWAMATA Shin;NISHISHITA Naoki |
分类号 |
C12N5/00 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells, comprising contacting a pigment epithelium-derived factor with the differentiated cell population. |
地址 |
Kobe-shi JP |