发明名称 CELL SORTING METHOD
摘要 The invention provides a method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells by contacting a pigment epithelium-derived factor with the differentiated cell population to induce apoptosis of the undifferentiated cells. The invention also provides an agent for cell transplantation therapy, containing a differentiated cell population substantially free of an undifferentiated cell, which is obtained by the method, as well as an agent for inducing apoptosis of an undifferentiated cell, containing a pigment epithelium-derived factor, and combined use of the aforementioned agent for cell transplantation therapy and the aforementioned agent for inducing apoptosis.
申请公布号 US2016040123(A1) 申请公布日期 2016.02.11
申请号 US201414780324 申请日期 2014.03.25
申请人 FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION 发明人 KANEMURA Hoshimi;GO Masahiro;KAWAMATA Shin;NISHISHITA Naoki
分类号 C12N5/00 主分类号 C12N5/00
代理机构 代理人
主权项 1. A method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells, comprising contacting a pigment epithelium-derived factor with the differentiated cell population.
地址 Kobe-shi JP