| 发明名称 |
INTRAOCULAR ANGIOGENESIS INHIBITOR AND USES THEREOF |
| 摘要 |
Intended is to provide a new therapeutic or prophylactic means for intraocular angiogenesis. Provided is an intraocular angiogenesis inhibitor including a polypeptide which is a variant of diphtheria toxin, and shows activity inhibiting binding between HB-EGF and an EGF receptor. |
| 申请公布号 |
US2016039890(A1) |
申请公布日期 |
2016.02.11 |
| 申请号 |
US201514622035 |
申请日期 |
2015.02.13 |
| 申请人 |
Hara Hideaki |
发明人 |
Hara Hideaki;Inoue Yuki |
| 分类号 |
C07K14/34;A61K38/16 |
主分类号 |
C07K14/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A prophylactic or therapeutic method for an ophthalmologic disease accompanied by intraocular angiogenesis, comprising a step of administering a polypeptide to a patient with ophthalmologic diseases accompanied by intraocular angiogenesis in a therapeutically effective amount, wherein the polypeptide is a variant of diphtheria toxin and shows activity of inhibiting binding between HB-EGF and an EGF receptor. |
| 地址 |
Gifu-shi JP |
