发明名称 |
STABLE AND SOLUBLE FORMULATIONS OF RECEPTOR TYROSINE KINASE INHIBITORS, AND METHODS OF PREPARATION THEREOF |
摘要 |
The present disclosure relates to stable formulations of receptor tyrosine kinase inhibitors (TKI), e.g., pazopanib; methods of preparation thereof; and use of the disclosed formulations in sustained delivery of the active agent to a target site. The disclosure further relates to methods of converting one polymorphic Form of a TKI to another polymorphic Form and/or an amorphous form. |
申请公布号 |
CA2957548(A1) |
申请公布日期 |
2016.02.11 |
申请号 |
CA20152957548 |
申请日期 |
2015.08.06 |
申请人 |
FORSIGHT VISION4, INC. |
发明人 |
HORVATH, JUDIT;ASTAFIEVA, IRINA;ERICKSON, SIGNE;FARINAS, KATHLEEN COGAN |
分类号 |
A61K31/4439 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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