COMPOSITION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK, COMPRISING ADK PROTEIN AS ACTIVE INGREDIENT

摘要

The present invention relates to a composition for preventing or treating sepsis or septic shock including a Mycobacterium tuberculosis -derived adenosine kinase (ADK) protein as an active ingredient. The Mycobacterium tuberculosis-derived ADK protein according to one exemplary embodiment of the present invention has an effect of inhibit binding between the LPS and cells by binding to LPS, and also has an excellent therapeutic effect against sepsis by enhancing viability in a sepsis animal model and suppressing inflammatory response in the lung and cell death in the spleen.