发明名称 |
PHARMACEUTICAL FORMULATIONS FOR SUBCUTANEOUS ADMINISTRATION OF FUROSEMIDE |
摘要 |
The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM. The present teachings can improve the stability of liquid pharmaceutical formulations including furosemide and the suitability of such pharmaceutical formulations for subcutaneous administration or delivery. |
申请公布号 |
EP2981258(A1) |
申请公布日期 |
2016.02.10 |
申请号 |
EP20140778339 |
申请日期 |
2014.04.03 |
申请人 |
SCPHARMACEUTICALS INC. |
发明人 |
MICHAELS, SCOTT, A.;MUNTENDAM, PIETER;LARSEN, GLENN, R. |
分类号 |
A61K31/341;A61K9/00;A61K9/08;A61K31/635;A61K47/02;A61K47/18;A61P9/04;A61P9/12 |
主分类号 |
A61K31/341 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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