| 摘要 |
Compounds of the formula <FORM:0877846/IV (b)/1> in which R1 represents a halogen atom or an alkyl group, R2 represents a hydrogen atom or an alkyl or alkoxy group, R represents a tertiary amino radical and n is the integer 2 or 3 are prepared by reacting an acid halide of the formula <FORM:0877846/IV (b)/2> with a tertiary amino alkylamine of the formula R(CH2)nNH2 to produce a basic acid amide, which may be converted to a salt or quaternary compound. In an example 2,6-dimethyl-4-ethoxybenzoyl chloride is reacted with diethylethylenediamine. Other products which may be obtained by reacting the acid halides with dialkylamino- and N-morpholinylethylamine and propylamines are listed. 2,6-dimethyl-4-alkoxy benzoyl chlorides may be prepared by etherifying a 2,6-dimethyl-4-hydroxy - bromobenzene, converting the bromine atom to a carboxyl group by a Grignard reaction, and reacting the resulting acid with thionyl chloride. A list of these hitherto unknown intermediates is given. 2-chloro-6-methyl benzoyl chloride may be prepared from the nitrile. |
