发明名称 花粉症ワクチンの治療効果を予測するバイオマーカー
摘要 <P>PROBLEM TO BE SOLVED: To provide a technology for effectively predicting effectiveness of a vaccine therapy to pollinosis such as cedar pollen allergy using a pollen allergen. <P>SOLUTION: A method for predicting effectiveness of a vaccine therapy to pollinosis using a pollen allergen includes (1) measuring change of expression of at least one gene selected from the group consisting of CCL2, IGHA1 and NCF1 in a mononucleosis cell isolated from a subject by the application of the vaccine therapy to the subject using the pollen allergen, and (2) correlating the change of expression measured in the (1) and the effectiveness of the vaccine therapy to pollinosis using the pollen allergen. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP5858418(B2) 申请公布日期 2016.02.10
申请号 JP20110076653 申请日期 2011.03.30
申请人 国立大学法人 千葉大学;公益財団法人かずさDNA研究所 发明人 岡本 美孝;稲嶺 絢子;堀口 茂俊;櫻井 大樹;中山 俊憲;野中 謙;山下 政克;小原 收
分类号 C12Q1/68;G01N33/53;G01N37/00 主分类号 C12Q1/68
代理机构 代理人
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