发明名称 |
PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION, CONTAINING DONEPEZIL |
摘要 |
The present invention relates to a composition for parenteral administration, containing donepezil as an active ingredient, and a preparation method therefor. Donepezil, which has been conventionally used for oral or transdermal administration, is prepared as microparticles comprising a biodegradable and biocompatible polymer and a release controller so as to be provided as a pharmaceutical composition for sustained release parenteral administration, thereby enabling in vivo sustained release continuously for 2-12 weeks or more. Therefore, it is possible to reduce the frequency of administration to a patient and maintain an effective concentration in the blood for a long time. |
申请公布号 |
EP2982367(A1) |
申请公布日期 |
2016.02.10 |
申请号 |
EP20140779696 |
申请日期 |
2014.04.02 |
申请人 |
DONGKOOK PHARMACEUTICAL CO., LTD. |
发明人 |
LEE, DEOK KEUN;KO, SUNG JIN;EOM, SHIN;CHA, KYUNG HOI |
分类号 |
A61K9/16;A61K31/445 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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