发明名称 NMRによる定量分析を用いた分配係数の測定方法
摘要 <P>PROBLEM TO BE SOLVED: To solve a problem that a conventional method for measuring a partition coefficient puts a heavy load on the environment because requiring a large amount of compounds for preparation of a calibration curve, which is necessary for quantification of compounds in a water phase and in an organic phase, and is disadvantageous in simplicity and quickness because of a heavy work load and does not allow the use of compounds absorbing ultraviolet rays a little or not absorbing ultraviolet rays at all in the case of measurement using an HPLC including a UV detector or an ultraviolet-visible absorption spectroscope. <P>SOLUTION: NMR is used to quantify compounds in a water phase and an organic phase to solve the problem. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP5858515(B2) 申请公布日期 2016.02.10
申请号 JP20110041393 申请日期 2011.02.28
申请人 杏林製薬株式会社 发明人 船田 恵子;福田 守
分类号 G01N24/08;G01R33/28;G01R33/30 主分类号 G01N24/08
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