发明名称 conjugados de epsilon-polilisina e o emprego dos mesmos
摘要 Conjugate comprises at least one carboxyl group-containing compound and an oligomer, where the oligomer: comprises peptidically crosslinked monomer units; is formed from more than 50%, relative to the number of monomer units, of epsilon -lysine monomer units; or comprises at least 10 consecutive monomer units that are formed from at least up to 70%, relative to the number of monomer units, of epsilon -lysine monomer units. Independent claims are included for: (1) the preparation of the conjugate comprising providing the oligomers, as above per se, and conjugating at least one optionally activated carboxylic group-containing compound to the oligomer; and (2) a kit, for preparing pharmaceutical composition (preferably a therapeutic or image enhancing composition), comprising the above conjugate.
申请公布号 BR112012001260(A2) 申请公布日期 2016.02.10
申请号 BR20121101260 申请日期 2010.07.09
申请人 MERCK PATENT GMBH 发明人 ARMIN KUEBELBECK;BARBRO BEIJER;GREGOR LARBIG;UWE HABERKORN;WALTER MIER
分类号 A61K47/48;A61K49/08;A61K51/04 主分类号 A61K47/48
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