摘要 |
The invention relates to a novel method and novel compounds for the preparation of clevidipine butyrate, a very short acting hypertensive calcium antagonist, as well as the synthesis of these new compounds useful for the preparation of clevidipine (also known as clevidipine butyrate). Moreover the invention also discloses new polymorphic forms of clevidipine butyrate, useful for the preparation of pharmaceutical compositions, and processes to prepare them. |