发明名称 |
INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ |
摘要 |
A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA of type A/California/04/09 in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein of type A/California/04/09 and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA of type A/California/04/09 as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. |
申请公布号 |
CA2730185(C) |
申请公布日期 |
2016.02.09 |
申请号 |
CA20092730185 |
申请日期 |
2009.07.02 |
申请人 |
MEDICAGO INC. |
发明人 |
D'AOUST, MARC-ANDRE;COUTURE, MANON;ORS, FREDERIC;TREPANIER, SONIA;LAVOIE, PIERRE-OLIVIER;DARGIS, MICHELE;VEZINA, LOUIS-PHILIPPE;LANDRY, NATHALIE |
分类号 |
C12N15/82;A61K39/145;A61P31/16;C07K14/11;C07K16/10;C12N5/10;C12N7/00;C12N7/01;C12N15/44 |
主分类号 |
C12N15/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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