Methods and systems for processing samples on porous substrates

摘要

Methods and systems for processing samples fixed to a porous substrate generally comprising, a compressor defining one or more fluid isolation areas, a support, for the porous substrate, having an opening corresponding to one or more of the fluid isolation areas of the compressor, an actuator that causes at least a portion of the compressor to press against the porous substrate, a fluid inlet having access to the fluid isolation area at least when the compressor is pressed against the porous substrate, and a fluid outlet to receive fluid, through the opening in the support corresponding to the fluid isolation area of the compressor, at least when the compressor is pressed against the porous substrate.

主权项

1. A system for processing samples fixed to a porous substrate comprising,
a compressor comprising a first portion and a second portion and defining a fluid isolation area when the first portion and the second portion are actuated against a porous substrate; a support having an opening corresponding to one or more of the fluid isolation areas of the compressor; an actuator that actuates the compressor to move one or both of the first and second portions to isolate only a portion of the porous substrate in the fluid isolation areas; a fluid inlet in the first portion in fluid communication with the fluid isolation area; and a fluid outlet in the second portion in fluid communication with the fluid isolation area to receive fluid from the fluid isolation area of the compressor, at least when the compressor is pressed against the porous substrate.