发明名称 |
Proceso de formación de un comprimido y aparato adecuado para la aplicación de dicho proceso |
摘要 |
The present invention pertains to a process for the preparation of a fast-disintegrating tablet (30) containing a medicinal substance, comprising the steps of providing a fluid formulation comprising the medicinal substance, providing a solid element (100) having formed therein at least one cavity, (101) cooling the solid element (100) to a temperature below a freezing temperature of the formulation, filling the cavity with the fluid formulation, solidifying the formulation while present in the cavity (101) to form a solid pellet comprising the medicinal substance without actively shaping the entire surface of the pellet, taking the pellet out of the cavity and drying the pellet in a vacuum to obtain the tablet. The invention also pertains to a system for performing such a process and a package containing the resulting tablet. |
申请公布号 |
ES2558852(T3) |
申请公布日期 |
2016.02.09 |
申请号 |
ES20100718551T |
申请日期 |
2010.04.28 |
申请人 |
Intervet International B.V. |
发明人 |
MIDDELBEEK, Hans Almer;SMIT, Jozefus A. C. |
分类号 |
A61J3/06;A61K9/00;A61K9/20;F26B5/06 |
主分类号 |
A61J3/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|