发明名称 Tissue adhesive with accelerated curing
摘要 The present invention relates to a polyurea system encompassing as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which can in particular have a number average molecular weight of ≧400 g/mol and an average OH functionality of 2 to 6, as component B) amino-functional compounds of general formula (I) in which X is an organic residue comprising a tertiary amino function, having no Zerewitinoff active hydrogen, R1 is a CH2—COOR3 residue, in which R3 is an organic residue having no Zerewitinoff active hydrogen, a linear or branched C1 to C4 alkyl residue, a cyclopentyl or cyclohexyl residue or H, R2 is an organic residue having no Zerewitinoff active hydrogen, n is an integer ≧2 or ≦3, in particular for closing, binding, bonding or covering cell tissue, and to a metering system for the polyurea system according to the invention.;
申请公布号 US9254347(B2) 申请公布日期 2016.02.09
申请号 US201214112132 申请日期 2012.04.17
申请人 Medical Adhesive Revolution GmbH 发明人 Heckroth Heike;Eggert Christoph
分类号 C08G18/32;C08G18/38;C08G18/10;A61L24/04;A61B17/03;C09J175/02;A61M5/19;C08G18/12;C08G18/73;A61L24/00;A61B17/00 主分类号 C08G18/32
代理机构 Drinker Biddle & Reath LLP 代理人 Drinker Biddle & Reath LLP
主权项 1. A polyurea system comprising as component A) an isocyanate-functional prepolymer obtained by reacting an aliphatic isocyanate A1) witha polyol A2), and as component B) an amino-functional compound of general formula (I) in which X is a residue of formula (II) wherein R4, R5, R6 are, each independently of one another or simultaneously, a methyl, ethyl, propyl or butyl residue, having no Zerewitinoff active hydrogen, wherein at least two of R4, R5, R6 are a methylene, ethylene, propylene, or butylene residue, having no Zerewitinoff active hydrogen,R1 is a linear or branched C1 to C4 alkyl residue, a cyclopentyl or cyclohexyl residue, H, or a CH2—COOR3 residue, in which R3 is an organic residue having no Zerewitinoff active hydrogen,R2 is a linear or branched C1 to C10 organic residue having no Zerewitinoff active hydrogen, andn is 2 or 3.
地址 Aachen DE