发明名称 |
Tissue adhesive with accelerated curing |
摘要 |
The present invention relates to a polyurea system encompassing as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which can in particular have a number average molecular weight of ≧400 g/mol and an average OH functionality of 2 to 6, as component B) amino-functional compounds of general formula (I) in which X is an organic residue comprising a tertiary amino function, having no Zerewitinoff active hydrogen, R1 is a CH2—COOR3 residue, in which R3 is an organic residue having no Zerewitinoff active hydrogen, a linear or branched C1 to C4 alkyl residue, a cyclopentyl or cyclohexyl residue or H, R2 is an organic residue having no Zerewitinoff active hydrogen, n is an integer ≧2 or ≦3, in particular for closing, binding, bonding or covering cell tissue, and to a metering system for the polyurea system according to the invention.; |
申请公布号 |
US9254347(B2) |
申请公布日期 |
2016.02.09 |
申请号 |
US201214112132 |
申请日期 |
2012.04.17 |
申请人 |
Medical Adhesive Revolution GmbH |
发明人 |
Heckroth Heike;Eggert Christoph |
分类号 |
C08G18/32;C08G18/38;C08G18/10;A61L24/04;A61B17/03;C09J175/02;A61M5/19;C08G18/12;C08G18/73;A61L24/00;A61B17/00 |
主分类号 |
C08G18/32 |
代理机构 |
Drinker Biddle & Reath LLP |
代理人 |
Drinker Biddle & Reath LLP |
主权项 |
1. A polyurea system comprising
as component A) an isocyanate-functional prepolymer obtained by reacting
an aliphatic isocyanate A1) witha polyol A2), and as component B) an amino-functional compound of general formula (I) in which
X is a residue of formula (II) wherein R4, R5, R6 are, each independently of one another or simultaneously, a methyl, ethyl, propyl or butyl residue, having no Zerewitinoff active hydrogen, wherein at least two of R4, R5, R6 are a methylene, ethylene, propylene, or butylene residue, having no Zerewitinoff active hydrogen,R1 is a linear or branched C1 to C4 alkyl residue, a cyclopentyl or cyclohexyl residue, H, or a CH2—COOR3 residue, in which R3 is an organic residue having no Zerewitinoff active hydrogen,R2 is a linear or branched C1 to C10 organic residue having no Zerewitinoff active hydrogen, andn is 2 or 3. |
地址 |
Aachen DE |