发明名称 |
Kits and methods for the treatment of cancer using gliadin peptides |
摘要 |
Kits and methods for treating cancer comprising administration of a gliadin peptide to a patient are disclosed herein. A kit according to the invention comprises a pharmaceutical composition comprising a gliadin peptide and instructions for administering the peptide to a patient. The kit may further comprise a pharmaceutical composition comprising at least one chemotherapeutic agent such as a receptor tyrosine kinase inhibitor and instructions for co-administering the compounds. A method of treating cancer according to the invention comprises administering a gliadin peptide to a patient and may further comprise co-administering at least one chemotherapeutic agent such as a receptor tyrosine kinase inhibitor. Co-administration of a gliadin peptide and receptor tyrosine kinase inhibitor to a patient with cancer is effective to decrease or prevent resistance of the cancer to the receptor tyrosine kinase inhibitor. |
申请公布号 |
US9254308(B2) |
申请公布日期 |
2016.02.09 |
申请号 |
US201414200585 |
申请日期 |
2014.03.07 |
申请人 |
BARMARSA RESEARCH LLC |
发明人 |
Shaw Fred L. |
分类号 |
A61K36/899;A61K31/282;A61K31/517;A61K35/74;A61K38/16;A61B6/00;A61P35/00;B82Y5/00;A61K38/10;A61K45/06;A61K35/744;A61K31/513;A61K31/5377;A61K33/24 |
主分类号 |
A61K36/899 |
代理机构 |
Marshall, Gerstein & Borun LLP |
代理人 |
Marshall, Gerstein & Borun LLP |
主权项 |
1. A method of treating cancer comprising administering a therapeutically effective amount of a gliadin peptide to a patient with cancer, wherein the gliadin peptide comprises the amino acid sequence set forth in SEQ ID NO:1 and is administered in a composition that does not contain an additional chemotherapeutic agent, wherein the cancer is non-small cell lung cancer. |
地址 |
Inverness IL US |