Method for treatment of acne using pharmaceutical compositions of clindamycin

摘要

The present invention relates to a method for treating, reducing or preventing acne. In particular, the present invention relates to methods for reducing the total number, incidence and severity of acne lesions on the skin which includes both inflammatory and non-inflammatory lesions. Further, the invention relates to reducing the incidence and severity of adverse events resulting from topical application of anti-acne agents resulting in improvement of skin tone. The method includes administering a novel and stable topical anti-acne pharmaceutical composition.

主权项

1. A method for treating acne by administering a topical pharmaceutical nanogel composition of clindamycin or a salt thereof, the nanogel composition consisting of a nanoemulsion and a gel base, the nanoemulsion consists of nano size droplets of clindamycin or a salt thereof, 5% to 25% w/w oils/lipids, 0.1% to 10% w/w of emulsifiers and one or more pharmaceutically acceptable excipients consisting of initiators, pH adjusting agents, thickening agents, emollients, humectants, preservatives, and chelating agents.