METHOD FOR PRODUCING 2-(BENZYLSULFINYL)-1-CYCLOALKENE-1-CARBOXYLIC ACID ESTER

摘要

PROBLEM TO BE SOLVED: To provide a method for producing a 2-(benzylsulfinyl)-1-cycloalkene-1-carboxylic acid ester in a high yield with reduced by-products.SOLUTION: The 2-(benzylsulfinyl)-1-cycloalkene-1-carboxylic acid ester is obtained by a method comprising: obtaining 2-(benzylsulfanyl)-1-cycloalkene-1-carboxylic acid ester by adding 1 to 1.5 pts.mole of phenylmethanethiol to 1 pt.mole of a (2-oxocycloalkane)-1-carboxylic acid ester at a temperature of -5°C to 15°C over a 0.5 to 10 hr period; and subsequently adding 1 to 3 pts.mole of aqueous hydrogen peroxide to 1 pt.mole of 2-(benzylsulfanyl)-1-cycloalkene-1-carboxylic acid ester at a temperature of 50°C to 80°C over a 5 to 10 hr period.SELECTED DRAWING: None