The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
申请公布号
HK1207568(A1)
申请公布日期
2016.02.05
申请号
HK20150108214
申请日期
2015.08.25
申请人
AVALANCHE AUSTRALIA PTY LTD.
发明人
CONSTABLE, IAN, J.;RAKOCZY, P. ELIZABETH;LAI, CHOOI-MAY;CHALBERG, THOMAS, W., JR.