| 发明名称 |
Paper-Based Reference Electrode And Potentiometric Ion Sensing |
| 摘要 |
Microfluidic, electrochemical devices are described. The microfluidic, electrochemical device may include a sample zone on a first porous, hydrophilic layer, a reference zone and a microfluidic channel, wherein the microfluidic channel provides for predominantly diffusive fluid communication between the sample zone and the reference zone; (therefore realizing a similar function of a reference electrode), a fluid-impermeable material that defines each of the sample zone, reference zone and microfluidic channel, a first electrode in fluid communication with the sample zone and a second electrode in fluid communication with the reference zone. Also described are microfluidic, electrochemical devices containing an ion-selective membrane for potentiometric ion sensing. |
| 申请公布号 |
US2016033438(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
US201414777051 |
申请日期 |
2014.03.03 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE ;REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
LAN Wenjie;MAXWELL Elizabeth Jane;PAROLO Claudio;BWAMBOK David;THUO Martin Mwangi;SUBRAMANIAM Anand Bala;WHITESIDES George M.;ZOU Xu U.;HU Jinbo;BUHLMANN Philippe;HAMEDI Mahiar Max |
| 分类号 |
G01N27/30;B01L3/00;G01N27/416 |
主分类号 |
G01N27/30 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A microfluidic, electrochemical device comprising
a first porous, hydrophilic layer comprising a sample zone; a hydrophilic region comprising a reference zone; and a microfluidic channel, wherein the microfluidic channel provides for predominantly diffusive fluid communication between the sample zone and the reference zone; a fluid-impermeable material that defines each of the sample zone, reference zone and microfluidic channel; a first electrode in fluid communication with the sample zone; and a second electrode in fluid communication with the reference zone. |
| 地址 |
Cambridge MA US |
