发明名称 |
BIOMARKERS OF IMMUNOMODULATORY EFFECTS IN HUMANS TREATED WITH ANTI-CD200 ANTIBODIES |
摘要 |
The present disclosure relates to anti-CD200 antibodies (e.g., variant anti-CD200 antibodies having decreased or no effector function) and to biomarkers for use in a variety of diagnostic and therapeutic methods, e.g., determining whether a human has been administered one or more of the antibodies at a dose sufficient to induce a desired immunomodulatory effect in the human and/or selecting an appropriate dosing schedule for a patient. |
申请公布号 |
US2016033514(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
US201514827693 |
申请日期 |
2015.08.17 |
申请人 |
ALEXION PHARMACEUTICALS, INC. |
发明人 |
MCKNIGHT Susan Faas;COFIELL Roxanne;YAN Yan |
分类号 |
G01N33/574;G01N33/50 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Cheshire CT US |