| 发明名称 |
PROCESS FOR PREPARATION OF 3-((2S,5S)-4-METHYLENE-5-(3-OXOPROPYL)TETRAHYDROFURAN-2-YL)PROPANOL DERIVATIVES AND INTERMEDIATES USEFUL THEREOF |
| 摘要 |
Discloses is a process for preparation of a compound of formula 7, or a derivative thereof, wherein PG1 is an alcohol protecting group. Also, disclosed are intermediates and processes for their preparation. The compound of formula 7 can be useful in the preparation of halinchondrin analogs such as Eribulin.; |
| 申请公布号 |
US2016031900(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
US201514882845 |
申请日期 |
2015.10.14 |
| 申请人 |
ALPHORA RESEARCH INC. |
发明人 |
SOUZA Fabio E.S.;BEXRUD Jason A.;ORPRECIO Ricardo;GORIN Boris |
| 分类号 |
C07D493/22;C07D493/04 |
主分类号 |
C07D493/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. The compound of formula 4 wherein PG1 is an alcohol protecting group. |
| 地址 |
Mississauga CA |
