| 发明名称 |
SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C |
| 摘要 |
This invention relates to a compound of formula I;;and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases. |
| 申请公布号 |
US2016031861(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
US201514814759 |
申请日期 |
2015.07.31 |
| 申请人 |
Boehringer Ingelheim International GmbH |
发明人 |
GRAUERT Matthias;ANDERSKEWITZ Ralf;BIXENMANN Achim;GRUNDL Marc;HAEBEL Peter Wilhelm;PAUTSCH Alexander |
| 分类号 |
C07D405/12;A61K45/06;C07D487/08;A61K31/4995;C07D487/10;A61K31/439;C07D405/14;A61K31/4439;C07D487/04;A61K31/407;A61K31/454;A61K31/496;A61K31/403 |
主分类号 |
C07D405/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of formula I wherein Cy denotes a group of formula Cy1 or Cy2, A denotes a 5 to 10 membered monocyclic, bicyclic or spirocyclic heterocycle containing 1 or 2 N-atoms, is or a salt thereof. |
| 地址 |
Ingelheim am Rhein DE |
