NORTH AMERICAN PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME (PRRS) VIRUS AND USES THEREOF

摘要

PROBLEM TO BE SOLVED: To provide vaccines against the porcine reproductive and respiratory syndrome virus (PRRS), and a diagnostic kit to distinguish between naturally infected and vaccinated animals.SOLUTION: The invention produces: polynucleotide molecules derived from infectious RNA molecules encoded onto a PRRS viral genome ORF1a genetically modified to elicit an effective immunoprotective response to a PRRS virus in porcine animals; polypeptides thereof; and transfected host cells.SELECTED DRAWING: Figure 5