| 发明名称 |
NOVEL CHIRAL RESOLUTION OF 4-ARYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDINE-5-CARBOXYLIC ACID ESTERS |
| 摘要 |
The present invention relates to a process for the preparation of an enantiomerically pure of 4-phenyl-6-methyl-2-thiazol-2-yl-1,4-dihydropyrimidine-5-carboxylic acid ester of formula (la), wherein R1 is phenyl once, twice or more times substituted by halogen; R2 is C1_6alkyl. |
| 申请公布号 |
WO2016016196(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
WO2015EP67173 |
申请日期 |
2015.07.27 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. |
发明人 |
WANG, LIN;DU, ZHENGMING;YU, JIANHUA;CHEN, JUNLI;ZHANG, GUOCAI;SHE, JIN |
| 分类号 |
C07D417/04;C07B57/00 |
主分类号 |
C07D417/04 |
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