ANTI IL-3R ALPHA AGENTS AND USES THEREOF

摘要

The present disclosure provides antibodies and antigen binding fragments thereof that bind to an epitope within an interleukin-3 receptor α.

主权项

1. A compound that binds to an epitope within an interleukin (IL)-3Rα chain, the epitope comprising:
(A) residues positioned within each of the following regions:
(i) amino acid 51 of SEQ ID NO: 1;(ii) one or more of amino acids 58, 59 and/or 61 of SEQ ID NO: 1; and(iii) one or more of amino acids 84 and/or 89 of SEQ ID NO: 1: or (B) residues corresponding to amino acids 51 or 59 of SEQ ID NO: 1.