发明名称 Phenyl Carbamate Compounds for Use in Preventing or Treating Epilepsy or Epilepsy-Related Syndrome
摘要 The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable epilepsy or its related syndrome such as drug-resistant epilepsy, comprising the phenyl carbamate compound as an active ingredient, and a use of the phenyl carbamate compound for preventing and/or treating epilepsy or epilepsy-related syndrome.
申请公布号 US2016030382(A1) 申请公布日期 2016.02.04
申请号 US201414775189 申请日期 2014.03.11
申请人 BIO-PHARM SOLUTIONS CO., LTD. 发明人 Choi Yong Moon
分类号 A61K31/325 主分类号 A61K31/325
代理机构 代理人
主权项 1. A pharmaceutical composition for preventing or treating an epilepsy or a epilepsy-related syndrome comprising a phenyl carbamate compound represented by Chemical Formula 1 or a pharmaceutically acceptable salt thereof, as an active ingredient: wherein, X is a halogen, n, that means the number of substituent X, is an integer from 1 to 5, R1 is a linear or branched alkyl group of C1-C4, A is hydrogen or a carbamoyl group represented by B is hydrogen, a carbamoyl group represented bytrialkyl silyl groups, trialkylaryl silyl groups (wherein the total number of alkyl and aryl groups is three), or a trialkyl silyl ether group, wherein each alkyl group is independently selected from the group consisting of linear, branched, or cyclic C1-C4 alkyl groups, and each aryl group is independently selected from the group consisting of C5-C8 aryl groups, A and B are not carbamoyl derivatives at same time, and R2 and R3 may be the same as or different from each other, and independently selected from the group consisting of hydrogen, a linear or branched alkyl group of C1-C4, a cycloalkyl group of C3-C8, and benzyl group.
地址 Suwon-si, Gyeonggi-do KR