| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING FUNGAL AND BACTERIAL PATHOGENS |
| 摘要 |
The invention features fragments of the Candida cell surface proteins Als3 and Hyr1 and combinations thereof useful in immunizing a subject against fungal or bacterial infections or both. |
| 申请公布号 |
US2016030534(A1) |
申请公布日期 |
2016.02.04 |
| 申请号 |
US201414774557 |
申请日期 |
2014.03.14 |
| 申请人 |
LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER ;NOVADIGM THERAPEUTICS, INC. |
发明人 |
IBRAHIM Ashraf S.;YEAMAN Michael R.;FILLER Scott G.;EDWARDS, JR. John E.;HENNESSEY, JR. John P. |
| 分类号 |
A61K39/00;C07K16/14;A61K39/39;C07K14/40 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An isolated polypeptide optionally fused to a heterologous fusion partner, wherein the amino acid sequence of said polypeptide consists of an amino acid sequence having at least 95% identity to(SEQ ID NO: 2) KTI TGVFNSFNSLTWSNAATYNY KGPGTPTWNAVLGWSLDGTSASPGDTFTLNMPCVFKFTTS QTSVDLTAHGVKYATCQFQA GEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTG SSVDLEDSKCFTAGTNTVTF NDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLF VAPQCANGYTSGTMGFANTY GDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNG IFITYKNVPAGYRPFVDAYI SATDVNSYTLSYANEYTCAGGYWQRAPFTLRWTGYRNSDA GSNG.Als3 (Ser/Thr-Rich Sequence) |
| 地址 |
Torrance CA US |
